Question

Which statement holds true for hydroxyapatite?

(a) It binds to single stranded molecules more tightly than double stranded molecules

(b) It binds to linear molecules more tightly than circular molecules

(c) It binds to circular molecules more tightly than linear molecules

(d) It binds to double stranded molecules more tightly than single stranded molecules

I had been asked this question in final exam.

My question is based upon Cloning the cDNA and Specialized Libraries in chapter Libraries Construction of Genetic Engineering

Answer 1

Correct option is (d) It binds to double stranded molecules more tightly than single stranded molecules

To explain: Hydroxyapatite is the molecule which binds more tightly to the double stranded molecules than the single stranded molecules. This property is very useful in the process of enrichment of rare species.