+1 vote
in Enzyme Technology by (55.0k points)
The matrix selected during affinity chromatography must possess certain chemical groups.

(a) True

(b) False

This question was posed to me during a job interview.

The query is from Enzymes Purification topic in portion Enzymes Purification of Enzyme Technology

1 Answer

+2 votes
by (727k points)
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Best answer
Correct answer is (a) True

To elaborate: In affinity chromatography, the matrix must possess certain chemical groups which can be activated or modified in order to allow the chemical linkage of variety of ligands under conditions which are harmful to the matrix. Hence the above statement is true.

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