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Sometimes a gene which we want to clone is present on a particular chromosome. For this purpose, the chromosome should be in which phase?

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Sometimes a gene which we want to clone is present on a particular chromosome. For this purpose, the chromosome should be in which phase?

(a) Prophase

(b) Telophase

(c) Metaphase

(d) Anaphase

The question was posed to me during an interview for a job.

This intriguing question originated from Cloning the cDNA and Specialized Libraries topic in division Libraries Construction of Genetic Engineering

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Right choice is (c) Metaphase

Explanation: The chromosomes should be in metaphase state because then they will be in a condensed form and it would be easy to handle them.

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