Question

The minor change in amino acid sequence can lead to _______ effect on three dimensional structure and there _____ in the primary sequence.

(a) huge, may be no change

(b) no, may be huge change

(c) very less, is very less change

(d) huge, would be huge change

The question was asked during an online exam.

Question is taken from Choosing the Right Mutations, Database of Mutant Lines and Gene Disruption in section Modifications and Mutagenesis of Genetic Engineering

Answer 1

Correct option is (a) huge, may be no change

For explanation I would say: The minor change in the amino acid sequence can lead to a huge effect on the three dimensional structure and might also abolish its function. In the primary sequence, there might be no change.