Question

If ______ gene is there, the double crossover may leave ________ in the chromosome.

(a) linear, functional copy

(b) circular, functional copy

(c) linear, a non-functional copy

(d) circular, a non-functional copy

I had been asked this question during a job interview.

This question is from Choosing the Right Mutations, Database of Mutant Lines and Gene Disruption in portion Modifications and Mutagenesis of Genetic Engineering

Answer 1

Correct option is (b) circular, functional copy

The explanation is: If the disrupted gene is in a circular form, there is a possibility that the double crossover may still leave a functional copy in the chromosome.