Question

The inactivation of endogenous genes may also be helpful in directing the expression of the mutated gene in the absence of background expression of wild type gene.

(a) True

(b) False

I had been asked this question in an internship interview.

Question is from Choosing the Right Mutations, Database of Mutant Lines and Gene Disruption in portion Modifications and Mutagenesis of Genetic Engineering

Answer 1

Right option is (a) True

The explanation: Inactivation of endogenous genes is very useful. It can be used to direct the expression of the mutated gene in the absence of background expression of wild type gene.