Question

Down regulation of expression of endogenous genes by transformation with constructs that would generate sense RNA, rather than anti-sense RNA is known as ___________

(a) suppression

(b) co-suppression

(c) multisuppression

(d) anti-suppression

The question was posed to me in homework.

My question comes from Post-transcriptional Gene Silencing in portion Modifications and Mutagenesis of Genetic Engineering

Answer 1

Right option is (b) co-suppression

For explanation I would say: When anti-sense RNA is used in plants, a phenomenon observed is co-suppression. It is the down regulation of expression of endogenous genes by transformation with constructs that would generate sense RNA, rather than anti-sense RNA.