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Which of the following is false for lactate dehydrogenase (LDH)?

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in Enzyme Technology by (55.0k points)
Which of the following is false for lactate dehydrogenase (LDH)?

(a) It is a tetrameric enzyme

(b) It catalyzes reversible phosphorylation of creatinine to creatinine phosphate by ATP

(c) It has five isoenzymes

(d) It is made up of two polypeptides

I have been asked this question in a job interview.

The query is from Enzymes topic in chapter Enzymes of Enzyme Technology

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Correct choice is (b) It catalyzes reversible phosphorylation of creatinine to creatinine phosphate by ATP

To explain: “It catalyzes reversible phosphorylation of creatinine to creatinine phosphate by ATP.” This statement is not true for LDH, as LDH catalyzes L-lactate to pyruvate. The following statements are true for LDH:

• It is a tetrameric enzyme.

• It has five isoenzymes: LDH1, LDH2, LDH3, LDH4, LDH5.

• It is made up of two polypeptides: M-type (muscle) and H-type (heart).

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