Correct answer is (b) Damage of heart tissue
Best explanation: Predominant elevation of LDH2 and LDH3 is seen in cases of leukemia. Hence Leukemia is not a clinical application of creatine kinase, but lactate dehydrogenase enzyme. Following are the clinical application of creatine kinase isoenzyme:
• Hypothyroidism shows an elevation CK activity, majorly CK3.
• Damage of heart tissue from myocardial infraction may detected my increased level of CK2 in blood.
• Myopathy and dystrophy has elevated levels of CK3 in serum.