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Which of the following is a clinical application of pseudocholine esterase?

(a) Diabetic ketoacidosis

(b) Diagnosis of organophosphate poisoning

(c) Salivary gland disorders

(d) Ruptured ectopic pregnancy

The question was posed to me during an interview.

My query is from Clinical Significance of 5′ in portion Clinical Enzymology of Enzyme Technology

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Right option is (b) Diagnosis of organophosphate poisoning

To explain: “Diagnosis of organophosphate poisoning.” This is a clinical application of pseudocholine esterase. Following clinical condition shows an increase of amylase concentration:

• Severe diabetic ketoacidosis.

• Salivary gland disorders such as mumps, salivary calculi.

• Ruptured ectopic pregnancy.

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