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Excess of uric acid causes ________

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Excess of uric acid causes ________

(a) duodenal ulcer

(b) macroamylsemia

(c) gout

(d) sphincter of oddi

The question was posed to me in final exam.

Question is from Clinical Significance of 5′ in chapter Clinical Enzymology of Enzyme Technology

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The correct answer is (c) gout

Explanation: Excess of uric acid causes gout. In duodenal ulcer, the ampulla is involved in the inflammatory process thus blocking secretion of pancreatic juice into the duodenum. Macroamylasemia results due to increase in plasma amylase with decrease in urinary excretion. Sphincter of oddi results due to contraction of pancreatic duct sphincter.

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