Question

Defect in glucose-6-phosphate dehydrogenase leads to ________

(a) red cell hemolysis

(b) diagnosis of organophosphate poisoning

(c) salivary gland disorders

(d) ruptured ectopic pregnancy

This question was addressed to me in quiz.

My question is taken from Clinical Significance of Angiotensin Converting Enzyme and Glucose-6-phosphate Dehydrogenase in division Clinical Enzymology of Enzyme Technology

Answer 1

Correct option is (a) red cell hemolysis

Easiest explanation: Defect in glucose-6-phosphate dehydrogenase leads to red cell hemolysis. Diagnosis of organophosphate poisoning is a clinical application of pseudocholine esterase. Following clinical condition shows an increase of amylase concentration:

• Salivary gland disorders such as mumps, salivary calculi.

• Ruptured ectopic pregnancy.