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Which of the following is not a clinical condition associated with amylase?

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Which of the following is not a clinical condition associated with amylase?

(a) Liver disease

(b) Sphincter of oddi

(c) Macroamylsemia

(d) Pneumonia

This question was addressed to me in an interview for internship.

The query is from Clinical Significance of Amylase, Transaminase and Proteinases topic in chapter Clinical Enzymology of Enzyme Technology

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The correct answer is (a) Liver disease

The explanation: Following clinical conditions are associated with amylase:

• Sphincter of oddi: results due to contraction of pancreatic duct sphincter.

• Macroamylsemia: results due to increase in plasma amylase with decrease in urinary excretion.

• Due to increased plasma amylase activity, cerebral trauma, shock and pneumonia may occur.

Transaminases are sensitive markers of hepatocellular injury. The value of transaminases reaches a peak when the illness is maximum.

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