Question

Genetic deficiency of __________ digests the pulmonary tissue.

(a) α – amylase

(b) α – 1 antitrypsin

(c) Transaminase

(d) α – 2 macroproteinase

I had been asked this question in an internship interview.

I would like to ask this question from Clinical Significance of Amylase, Transaminase and Proteinases topic in portion Clinical Enzymology of Enzyme Technology

Answer 1

The correct choice is (b) α – 1 antitrypsin

Easiest explanation: Genetic deficiency of α -1 antitrypsin causes elastase to act on a host and digest the pulmonary tissue. α-amylase hydrolyzes α-1,4 linkages in starch and glycogen to yield maltase. Transaminase are the enzymes which are involved in transfer of aminoacids. α – 2 macroproteinase is an anti-proteinase which keeps a check on the activity of proteinases.