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Which of the following is not true for hyaluronidase?

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Which of the following is not true for hyaluronidase?

(a) It promotes rapid absorption of drug injected subcutaneously

(b) It has antibacterial action

(c) It increases tissue permeability

(d) It is used in the treatment of traumatic and postoperative edema

I have been asked this question in an international level competition.

My question is based upon Therapeutic and Analytical Uses of Enzymes topic in chapter Enzymes of Enzyme Technology

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Correct answer is (b) It has antibacterial action

Easy explanation: “It has antibacterial action.” This is a false statement. It is true in the case of lysozyme and is used in eye infection for treatment. Following statements are true for hyaluronidase:

• It promotes rapid absorption of drug injected subcutaneously.

• It increases tissue permeability by depolymerizing hyaluronic acid.

• It is used in the treatment of traumatic and postoperative edema.

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