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Which of the following do not show stereo specificity?

(a) L-lactate dehydrogenase

(b) Epimerase

(c) Salivary α-amylase

(d) L-glucose oxidase

This question was posed to me in an international level competition.

Question is taken from Specificity of Enzyme Action in portion Enzymes of Enzyme Technology

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The correct choice is (b) Epimerase

Explanation: Stereo specificity is one in which the enzymes shows specificity towards only one type of isomers. L-lactate dehydrogenase, Salivary α-amylase and L-glucose oxidase shows stereo specificity toward L-lactic acid, α- 1,4 glycoside linkage and L-glucose respectively. Epimerase and isomerase do not show stereo specificity.

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