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Which of the following enzyme is not used to diagnose hepatobiliary disease?

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Which of the following enzyme is not used to diagnose hepatobiliary disease?

(a) Alkaline phosphatase

(b) Alanine aminotransferase

(c) γ-glutamyl transferase

(d) 5^I – nucleotidase

The question was posed to me in a job interview.

Asked question is from Diagnostic Use of Enzymes topic in section Enzymes of Enzyme Technology

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Right option is (b) Alanine aminotransferase

Explanation: Alanine aminotransferase is located in liver, skeletal muscle and heart. It is used to diagnose hepatic parenchymal disease. Alkaline phosphatase, γ-glutamyl transferase and 5^I – nucleotidase are used in the diagnosis of hepatobiliary disease.

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