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LDH4 and LDH5: Bacterial meningitis:: LDH1 and LDH3: ___________

(a) Kidney malignancies

(b) Myocardial infarction

(c) Intracranial hemorrhage

(d) Viral meningitis

The question was posed to me in an international level competition.

My question comes from Enzymes topic in section Enzymes of Enzyme Technology

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Right option is (d) Viral meningitis

For explanation: An elevation of LDH4 and LDH5 is CSF is seen cases of bacterial meningitis. In the same way, an elevation of LDH1 through LDH3 is seen in cases of viral meningitis. LDH activity in urine is seen in cases of kidney malignancies. Myocardial infarction is indicated when there is an increase in serum level of LDH1 relative to LDH2. In neonates, elevation LDH-CSF is observed in cases of intracranial hemorrhage.

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