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Which one of the following will travel fastest through the gel if the amount of DNA present is same in all?

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in Genetic Engineering by (118k points)
Which one of the following will travel fastest through the gel if the amount of DNA present is same in all?

(a) Circular

(b) Supercoiled

(c) Nicked

(d) Supercoiled and circular will move at same speed and faster than nicked

This question was addressed to me in an online interview.

My question is taken from Gel electrophoresis, Oligonucleotide  & Microarrays in portion Basics of Genetic Engineering of Genetic Engineering

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Right answer is (b) Supercoiled

For explanation I would say: The supercoiled form of DNA will travel the fastest. It is so because; the movement through the gel is based on the size. The smaller the molecule is the less retarding force it experiences when it moves. Hence, supercoiled which is having the smallest size will move the fastest.

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