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Which of the following is not true for macroamylase?

(a) Presence of macroamylase in the serum is referred to as macroamylsemia

(b) Macroamylase is formed by binding of ordinary S type amylase with IgG, IgA or other normal –abnormal high molecular weight proteins

(c) Macroamylsemia is not symptomless

(d) Macroamylase causes a harmless condition which may be confused with other causes of hyperamylasemia

This question was posed to me by my school principal while I was bunking the class.

Question is from Diagnostic Use of Enzymes topic in section Enzymes of Enzyme Technology

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Right option is (c) Macroamylsemia is not symptomless

To explain: “Macroamylsemia is not symptomless.” This statement is false because it is symptomless. The statements which are true for macroamylase are as follows:

• Presence of macroamylase in the serum is referred to as macroamylsemia.

• Macroamylase is formed by binding of ordinary S type amylase with IgG, IgA or other normal –abnormal high molecular weight proteins.

• Macroamylase causes a harmless condition which may be confused with other causes of hyperamylasemia.

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