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Miachelis Menten model is also referred to as “rapid equilibrium model”.

(a) True

(b) False

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This intriguing question originated from Kinetics of Enzyme Catalysed Reaction in division Enzyme Kinetics of Enzyme Technology

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The correct answer is (a) True

The explanation: The main difference between Henri and Miachelis Menten model is that Miachelis and Menten did a strong experimental work to prove that any enzyme catalyzing single substrate reaction will possess a hyperbolic curve. The unique feature of this model is assumption of rapid equilibrium between reactants and ES complex, where the ES complex will slowly decompose to form free enzyme and products. Hence it is appropriate to term this model as “rapid equilibrium model”. Hence the above statement is true.

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