Question

Generation of recombinants by randomly cloning fragments of total DNA from an organism is called as __________

(a) genomic library

(b) screening

(c) recombination

(d) shotgun cloning

This question was posed to me in examination.

This intriguing question comes from Cloning using a Simple Plasmid and Alpha Complementation in section Simple Cloning of Genetic Engineering

Answer 1

Right answer is (d) shotgun cloning

The explanation: Generation of recombinants by randomly cloning the fragments of total DNA from an organism is called as shotgun cloning. Collection of such fragments is known as a library.