Question

Choose the correct statement for rifampcin.

(a) It inactivates both E. coli polymerase and T7 polymerase

(b) It activates both E. coli polymerase and T7 polymerase

(c) It inhibits T7 polymerase but doesn’t inhibits E. coli polymerase

(d) It inhibits E. coli polymerase but doesn’t inhibits T7 polymerase

I had been asked this question by my college director while I was bunking the class.

I'm obligated to ask this question of Promoters topic in portion Use of Cloned DNA of Genetic Engineering

Answer 1

Correct option is (d) It inhibits E. coli polymerase but doesn’t inhibits T7 polymerase

The best I can explain: Rifampcin is added in order to reduce the transcription of other genes. It inhibits the E. coli RNA polymerase but doesn’t inhibit the T7 polymerase.