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Which of these is not a cofactor?

(a) Folic acid

(b) Nickel

(c) Biotin

(d) Coenzyme A

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I want to ask this question from Enzymes in portion Enzymes of Enzyme Technology

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The correct option is (b) Nickel

Explanation: Nickel is a cofactor that is used by urease enzyme. Additional non protein chemical component required for optimum activity of enzymes is referred to as cofactors. Coenzyme is referred to as a complex organic or metallo-organic compound present in an enzyme. Cofactors are folic acid, biotin, coenzyme A, etc.

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