Question

Which of the following is a semi-synthetically derived hypocholesterolemic agent?

(a) Simvastatin

(b) Lovastatin

(c) Mevastatin

(d) Pravastatin

I have been asked this question during an interview.

This interesting question is from Non-Food Applications topic in section Fermenting Vegetables & Milk, Fermenting Sour Tonic Beverages, Non-Food Applications of Fermentation of Fermentation Technology

Answer 1

Correct option is (a) Simvastatin

For explanation I would say: Simvastatin is a semi-synthetically derived hypocholesterolemic agent. It is derived from lovastatin. It is used to lower the lipid content from the body and thus helps in losing the weight. Lovastatin, mevastatin, and pravastatin are produced by respective strains of fungi.