Right option is (c) Ferrocenes
For explanation: Ferrocenes represent a commonly used family of mediators. An extreme case of this amplification is the detection of ADP. ADP is the added analyte and excess glucose, phosphoenol pyruvate, NADH and oxygen are present to ensure maximum reaction. Four enzymes such as hexokinase, pyruvate kinase, lactate dehydrogenase and lactate oxidase are co-immobilised within the packed bed reactor.