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_____________ measures protein interaction in real time without any labelling technique.

(a) Calorimetric biosensor

(b) Surface Plasmon Resonance biosensor

(c) Penicillin measuring biosensor

(d) Portable biosensor

I had been asked this question during a job interview.

Question is from Application of Biosensors topic in division Biosensors of Enzyme Technology

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The correct answer is (b) Surface Plasmon Resonance biosensor

The best I can explain: Surface Plasmon Resonance biosensor measures protein interaction in real time without any labelling technique. It measures optical changes. Calorimetric biosensor is used to measure heat dissipated in a reaction by using thermistors. Penicillin measuring biosensor consists of a silicon wafer pH sensitive layer on which penicillinase enzyme is immobilized. Portable biosensors are those which can be carried anywhere.

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