Question

Which of the following rule belongs to optimization of the two-phase system for enzyme-catalyzed reactions?

(a) The difference between the Log P values of the products and the organic phase should be as small as possible

(b) Allows to be used with low molecular weight hydrophilic coenzymes with the assistance of a coenzyme regenerating process

(c) Allowing efficient and continuous use of biphasic PBRs as long as the moving organic phase is saturated with water

(d) Allowing efficient and continuous use of biphasic PBRs

The question was posed to me by my school teacher while I was bunking the class.

My question is taken from Recent Advances in chapter Recent Advances in Enzyme Technology of Enzyme Technology

Answer 1

Right answer is (a) The difference between the Log P values of the products and the organic phase should be as small as possible

The best explanation: The concept of Log P being extended to cover the substrates, products and the interphase is used for optimization of the two-phase system for enzyme-catalyzed reactions. The difference between the Log P values of the products and the organic phase should be as small as possible, whereas the Log P values are much greater than that of products and interphase which helps in encouraging the transfer of the product from the aqueous phase through the interphase into the organic phase, after the reaction.