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The conversion of porcine insulin to human insulin is catalyzed by ________ enzyme.

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The conversion of porcine insulin to human insulin is catalyzed by ________ enzyme.

(a) thermolysin

(b) trypsin

(c) streptokinase

(d) asparginase

The question was posed to me during an online exam.

The origin of the question is Recent Advances topic in portion Recent Advances in Enzyme Technology of Enzyme Technology

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Right answer is (b) trypsin

Easiest explanation: The conversion of porcine insulin to human insulin is catalyzed by trypsin which replaces C-terminal alanine (β30) residue by a threonine. Thermolysin is used to produce aspartame from aspartic acid. Aspartate is produced from aspargine by using asparginase. Plasminogen is converted to plasmin by streptokinase enzyme.

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