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Termination codon is required for stopping high levels of transcription of other regions such as _______ which might interfere with ___________ of the vector.

(a) origin, replication

(b) end, replication

(c) end, stability

(d) origin, stability

This question was posed to me in an interview.

The query is from Expression in Vivo in section Use of Cloned DNA of Genetic Engineering

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Right choice is (d) origin, stability

The best I can explain: Termination codon is required for stopping high levels of transcription of other regions such as origin. Other regions might interfere with the stability of the vector.

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