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Choose the incorrect statement in respect to MACs.

(a) They are mammalian or human artificial chromosomes

(b) Large stretches of DNA (in excess of 100 kb) can be inserted

(c) A selectable marker is required

(d) It can be maintained for long term

The question was asked by my school teacher while I was bunking the class.

This intriguing question comes from Cultured Cells in Mammals and Restricted Areas in Intact Organisms in portion Using Other Organisms of Genetic Engineering

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Right option is (c) A selectable marker is required

The best I can explain: Nowdays, MACs have been developed and they are the mammalian or human artificial chromosomes. They can carry large stretches of DNA and can be maintained for long term without the requirement of being selected.

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