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Centromere is the most important component of the human artificial chromosome. It is constructed from tandemly repeated copies of 171 bp of ______ DNA sequence.

(a) alpha satellite

(b) beta satellite

(c) satellite 2

(d) satellite 1

The question was asked in exam.

This key question is from Cultured Cells in Mammals and Restricted Areas in Intact Organisms in section Using Other Organisms of Genetic Engineering

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Correct choice is (a) alpha satellite

For explanation: Centromere is the most important component of the human artificial chromosome. It is constructed from tandemly repeated copies of 171 bp of alpha satellite DNA sequence. There are other satellite DNA sequences such as beta, satellite 1 and 2.

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