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Resistance to bleomycin (zeocin) is used as a selectable marker for mammalian cultured cells and its function is ____________

(a) DNA damaging agent

(b) DNA synthesis promoter

(c) Inhibiting RNA synthesis

(d) Activating RNA synthesis

This question was addressed to me during a job interview.

I would like to ask this question from Cultured Cells in Mammals and Restricted Areas in Intact Organisms in division Using Other Organisms of Genetic Engineering

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Best answer
The correct option is (a) DNA damaging agent

The explanation: Resistance to bleomycin (zeocin) is used as a selectable marker for mammalian cultured cells and it is a DNA damaging agent. It does so by expression of a binding protein.

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