Question

Tetracycline binding repressor protein when fused to transcription activator protein from herpes simple virus, then it is called as transactivator protein (tTA).

(a) True

(b) False

This question was posed to me during a job interview.

My doubt stems from Cultured Cells in Mammals and Restricted Areas in Intact Organisms topic in portion Using Other Organisms of Genetic Engineering

Answer 1

Correct option is (a) True

To explain: Transactivator protein is the protein formed by fusion of tetracycline binding repressor protein to the transcription activator protein from herpes simple virus. The protein which is repressing originally transforms into activating in nature.