Question

In case of promoter-probe vectors, the same or related species should be as a vector whose DNA is to be screened.

(a) True

(b) False

I got this question in an international level competition.

This intriguing question originated from Reporter Genes topic in section Screening Libraries of Genetic Engineering

Answer 1

Right choice is (a) True

Explanation: For promoter-probe vectors, the same species should be used as a host for the vector whose DNA is to be screened. It is so because a gene which is a promoter in one species may not be a promoter in other gene and thus it becomes difficult to detect.