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The term ‘endonuclease’ refers to cutting the DNA sequence from ______________

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The term ‘endonuclease’ refers to cutting the DNA sequence from ______________

(a) only within the polynucleotide chain, not at the ends

(b) the ends of the chain

(c) anywhere in the chain

(d) exactly in the middle of the chain

I had been asked this question in exam.

The question is from Restriction Endonuclease & Phosphatases in section Basics of Genetic Engineering of Genetic Engineering

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Right answer is (a) only within the polynucleotide chain, not at the ends

Explanation: The cleavage is done within the polynucleotide chain and not at the ends. The enzyme which cuts the sequence at the ends is known as exonuclease.

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