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Purification of DNA by using silica derivatized groups by DEAE is termed as ____________

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Purification of DNA by using silica derivatized groups by DEAE is termed as ____________

(a) ion exchange resin based method.

(b) silica based purification

(c) atom based resin exchange method

(d) packed bed purification

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I need to ask this question from Purification of Plasmid DNA topic in chapter Basics of Genetic Engineering of Genetic Engineering

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The correct choice is (a) ion exchange resin based method.

Explanation: Silica derivatized groups by DEAE are used for purification of DNA. These groups are positively charged and the DNA gets attached to it, along with other species such as RNA which are negatively charged. Further, DNA can be obtained by varying the ionic concentrations.

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