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What reaction is represented in the diagram?

(a) Purine degradation pathway

(b) Oxidative step of pentose phosphate pathway

(c) Glycolysis

(d) TCA cycle

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This is a very interesting question from Clinical Significance of Angiotensin Converting Enzyme and Glucose-6-phosphate Dehydrogenase topic in section Clinical Enzymology of Enzyme Technology

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Right option is (b) Oxidative step of pentose phosphate pathway

Explanation: Pentose phosphate pathway has two steps: oxidative and non-oxidative. Oxidative step is represented in the following diagram. Glucose-6-phosphate is converted to 6-phosphoglucono-δ-lactone by glucose-6-phosphate dehydrogenase. This is converted to 6-phosphogluconate which is then converted to ribulose-5-phosphate by 6-phosphogluconate dehydrogenase. This is called oxidative decarboxylation.

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