Question

If the catalysis involves participation of small organic molecules, cofactors, and amino-acid side chains from the enzyme is termed as ____________

(a) specific acid base catalysis

(b) general acid base catalysis

(c) substrate collision theory

(d) lock and key model

The question was posed to me during an online exam.

My question is taken from Enzyme Kinetics topic in division Enzyme Kinetics of Enzyme Technology

Answer 1

Right choice is (b) general acid base catalysis

The best explanation: If the catalysis involves participation of small organic molecules, co-factors and amino-acids side chains from the enzyme is referred to as general acid-base catalysis. If the catalysis involves water molecules for proton donation or acceptance, the catalysis is referred to as general acid-base catalysis. Lock and key model is proposed by Emil Fischer in 1958. Substrate collision theory deals with binding between enzyme and substrate molecule.