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The leu1+ marker encodes which enzyme?

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The leu1+ marker encodes which enzyme?

(a) orotidine-5’-phosphate decarboxylase

(b) beta isopropylmalate dehydrogenase

(c) orotidine-5’-phosphate decarboxylase or beta isopropylmalate dehydrogenase

(d) orotidine-5’-phosphate decarboxylase & beta isopropylmalate dehydrogenase

This question was posed to me during an online interview.

This intriguing question comes from Other Systems topic in chapter Using Other Organisms of Genetic Engineering

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The correct answer is (b) beta isopropylmalate dehydrogenase

For explanation I would say: The leu1+ marker encodes beta isopropylmalate dehydrogenase. Orotidine-5’-phosphate decarboxylase is another selectable marker and is encoded by ura4+ gene.

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