Question

The ARG8m gene which produces an enzyme for arginine biosynthesis is located in _______ and is of ______ origin.

(a) mitochondrial, nuclear

(b) nuclear, mitochondrial

(c) nuclear, nuclear

(d) mitochondrial, mitochondrial

This question was addressed to me in an internship interview.

This intriguing question comes from Organelle Transformation in division Using Other Organisms of Genetic Engineering

Answer 1

The correct option is (a) mitochondrial, nuclear

To elaborate: The ARG8m gene which produces an enzyme for arginine biosynthesis is located in the mitochondria but is of nuclear origin. It is designed for expression in the mitochondrion and will confer the ability to grow in the absence of arginine.