Question

Ratio of plasma CK (MM3) and CK (MM1) is an indication of heart attack.

(a) True

(b) False

I got this question in an international level competition.

This question is from Clinical Significance of Trypsinogen and Creatine Kinase in section Clinical Enzymology of Enzyme Technology

Answer 1

Correct choice is (a) True

The explanation: CK (MM) has isoform CK (MM3) which is released from the cell and gets converted to CK (MM2) and CK (MM1). Later, CK (MM2) gets converted to CK (MM1). Hence the plasma CK (MM3) and CK (MM1) ratio is an indication of heart attack 2-5-hrs after the onset of chest pain.