Question

Which of the following factor does not favor peptide synthesis?

(a) Use of liquid/liquid biphasic systems

(b) Selection of protecting residues for amino and carboxyl groups

(c) Choice of pH

(d) Location of proteases

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Answer 1

Correct choice is (d) Location of proteases

The best explanation: The following factor favor peptide synthesis which acts by controlling the equilibrium of the reaction:

• Choice of pH.

• Selection of protecting residues for amino and carboxyl groups which favor product precipitation.

• Use of liquid/liquid biphasic systems.

Location of proteases is important for its choice of raw material to obtain it. Hence it is not a factor which favors peptide synthesis.