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Which of this is not true for ion-selective electrode?

(a) Determination of electrical potential at very high impedance

(b) Allowing zero current flow effectively

(c) Increasing the heat output

(d) Causing no interference with the reaction

I had been asked this question during an internship interview.

My question is based upon Potentiometric Biosensors topic in division Biosensors of Enzyme Technology

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Right choice is (c) Increasing the heat output

The explanation: Increasing the heat output is true in case of thermistors that are used in calorimetric biosensors. For ion-selective electrodes, the following statements are true:

• Determination of electrical potential at very high impedance,

• Allowing zero current flow effectively,

• Causing no interference with the reaction.

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