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Which of the following property is not possessed by biosensors?

(a) The probe used in the biosensor must be tiny and biocompatible, having no toxic or antigenic effects

(b) The biosensor should be cheap, small, portable and capable of being used by semi-skilled operators

(c) There should be a market for the biosensor

(d) The specificity of substrate binding is mediated by spatial arrangement of atoms in an enzyme’s substrate binding site as well as substrate.

This question was addressed to me during an internship interview.

Asked question is from Biosensors topic in section Biosensors of Enzyme Technology

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Right choice is (d) The specificity of substrate binding is mediated by spatial arrangement of atoms in an enzyme’s substrate binding site as well as substrate.

The best explanation: Following are the properties which a biosensor should possess:

• If the biosensor used in invasive, the probe must be tiny and biocompatible, having no toxic or antigenic effects.

• The biosensor should be cheap, small, portable and capable of being used by semi-skilled operators.

• If the traditional methods used is encouraged and the decentralization of laboratory testing is discouraged, then there is no use of producing more biosensors. Thus, there should be a market for the biosensor.

“The specificity of substrate binding is mediated by spatial arrangement of atoms in an enzyme’s substrate binding site as well as substrate.” This is a property of active site of the enzyme.

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