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Which of the following coenzyme is not derivatized by alkylation of the exocyclic N6-amino nitrogen of the adenine present in it?

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Which of the following coenzyme is not derivatized by alkylation of the exocyclic N6-amino nitrogen of the adenine present in it?

(a) Papain

(b) Coenzyme A

(c) NAD^+

(d) NADP^+

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The question is from Future Prospects topic in chapter Enzyme Technology Future Prospects of Enzyme Technology

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The correct answer is (a) Papain

Explanation: Papain is a protease enzyme which is used in meat tenderization. Coenzymes may be derivatized for adequate immobilization and regeneration which will activate coenzymes so that it attaches to the support and does not interfere with its biological function. Coenzyme derivatization involves the alkylation of the exocyclic N6-amino nitrogen of the adenine moiety present in the coenzymes NAD^+, NADP^+, NADH, NADPH, ATP and coenzyme A.

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