Question

___________ is produced by using immobilized Escherichia coli in batch or semi-continuous STR or PBR.

(a) Penicillin

(b) Ampicillin

(c) L-aspartic acid

(d) Urocanic acid

This question was addressed to me in semester exam.

My question comes from Immobilized Enzymes in division Immobilized Enzymes and their Uses of Enzyme Technology

Answer 1

Right choice is (a) Penicillin

To elaborate: Penicillin is produced by using immobilized Escherichia coli in batch or semi-continuous STR or PBR.  Ampicillin is produced by using immobilized Penicillin-G-amidase in a packed bed column. Immobilized aspartase may be prepared by entrapping Escherichia coli cells in a k-carageenan gel cross-linked with glutaraldehyde and hexamethylenediamine which helps in the production of L-aspartic acid. Immobilized histidase preparation consisting of heat-treated Achromobacter liquidum cells entrapped in a polyacrylamide gel which helps in conversion of L-histidine to urocanic acid.