Question

The equation \(t_{1/2}=\frac{0.693}{k_d}\) represents ___________

(a) Arrhenius equation

(b) Lineweaver Burk equation

(c) Half-life

(d) Gibbs-Helmholtz equation

I had been asked this question during an interview for a job.

This key question is from Enzyme Kinetics Fundamentals in division Enzyme Kinetics Fundamentals of Enzyme Technology

Answer 1

Right answer is (c) Half-life

For explanation: The above equation is representing half-life of an enzyme. Half-life of an enzyme is the time it takes for the activity to reduce to half of the original activity. Half-life is inversely proportional to rate of denaturation. Arrhenius equations describes the rate of an enzyme catalyzed reaction with an increase in temperature. Lineweaver Burk equation describes the rate of an enzyme catalyzed reaction. The relationship between the change in the pKa and the change in temperature is given by the Gibbs-Helmholtz equation.