Question

Once cosmids are inside the E.coli cells, they don’t generate phage but are propagated as plasmids.

(a) True

(b) False

The question was asked in semester exam.

This interesting question is from Lambda ZAP and Cosmids in portion Other Vector Systems for E of Genetic Engineering

Answer 1

The correct option is (a) True

For explanation I would say: Once cosmids are inside the E. coli cells, they don’t generate more phage but are propagated as plasmids. It is so because no more coat protein genes are present and thus it can’t be packaged. They can’t give rise to plaques.