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If colEI derived origin of replication is replaced by the origin of replication of F plasmid, it is called as:

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If colEI derived origin of replication is replaced by the origin of replication of F plasmid, it is called as:

(a) phagemid

(b) F cosmid

(c) plasmid

(d) fosmid

I have been asked this question in unit test.

Enquiry is from Lambda ZAP and Cosmids in portion Other Vector Systems for E of Genetic Engineering

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The correct answer is (d) fosmid

Explanation: If colE1 derived origin of replication is replaced by the origin of replication of F plasmid it is known as fosmid. F plasmids are present in a low copy number.

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